Current Flight Software (FSW) systems embed customized pieces of software to control spacecraft instrumentation. Because spacecraft contain unique hardware components, reusing software device drivers or higher-level FSW subsystems dependent on the drivers across different missions is difficult; and changing instrumentation for an FSW is complicated and time-consuming. This paper outlines an innovative approach to design software components that interact reliably with aerospace instruments and applications while promoting reuse and ease of change. As building blocks for a Flight Instruments Reuse & Standardization Library (FIRSL), the reusable software drivers are in the form of low-level devices or high-level composite devices for space-based missions. The paper also describes the proof of concept used to verify the results of applying the FIRSL design approach.